Which method of separation employs differences in boiling points of liquids?

The method of separation that utilizes differences in boiling points of liquids is distillation. This technique works by heating a liquid mixture to create vapor, which then cools and condenses back into a liquid form, effectively separating the components based on their individual boiling points. The component with the lower boiling point vaporizes first and can be collected separately, allowing for the purification and separation of substances in a liquid mixture.

In contrast, centrifugation relies on the centrifugal force to separate components of different densities, not boiling points. Filtration is a process for separating solids from liquids or gases by using a porous barrier, while chromatography separates substances based on their movement through a stationary phase, influenced by their interactions with both the stationary and mobile phases rather than boiling points. Thus, distillation is the appropriate choice for separating liquids based on their boiling point differences.